Composite Risk Index postmenopausal

Risk group

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5-year-disease free surival:
Risk Parameter estimate Letrozol Letrozol → Tamoxifen Tamoxifen → Letrozol Tamoxifen
Low risk <0.66 96% 94% 93% 94%
Intermediate Risk 0.66-1.53 90% 91% 93% 86%
High Risk >1.53 80% 76% 74% 69%
Graph:
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Link to Harvard Composite Risk STEPP: https://rconnect.dfci.harvard.edu/CompositeRiskSTEPP/









Please note: Premenopausal status was determined differently in TEXT and SOFT
TEXT: Premenopausal status was determined prior to chemotherapy (they started with chemotherapy and ovarian function supression at the same time)
SOFT: women were classified as premenopausal if they had premenopausal E2-Levels after chemotherapy (otherwise they were seen as postmenopausal)


Composite Risk Index - premenopausal

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8-year-freedom from distant recurrence:
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